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I have severe bone pain in my legs and frequent bowel movements up to fifteen times per day. parathyroid scan showed nothing abnormal. after taking methotrexate only three days i saw marked improvement. after 28 day trial, pain in the legs is 80% improved, (am a multiply operated spine patient so did not expect 100%). bowel movements are more normal and once per day as they should be. this shows with just one month of treatment, that i do have parathyroid disease that was not picked up on scans. now i can pursue treatment through surgery.
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I have read many bad reviews on this treatment, so let me tell you my positive one. i am early 60s, very active, slightly built and failed my bone density scan. did my research (very important) and found a fabulous young female rheumatologist. after viewing all of my prior dexa scans we tried one fosamax (i had been on evista for four years prior due to healed multiple ulcers). the fosamax reaction was very bad but the gastric distress eased up finally. we decided on the methotrexate infusion. the injection was pleasant, the people great. i went to work. had a headache for ...